Journal of Paramedical Sciences & Rehabilitation

Journal of Paramedical Sciences & Rehabilitation

Trend of antibiotic resistance of Escherichia coli strains isolated from urinary tract infections in outpatient patients from Zahedan

Document Type : Original Article

Authors
M keikha 1
M Rava 2
1 Department of Medical Microbiology, Isfahan Medical School Isfahan, Isfahan, Iran
2 B.Sc. in Laboratory Sciences, Nabi Akram Hospital. Zahedan, ZAhedan, Iran
10.22038/jpsr.2017.21755.1556
Abstract
Purpose:
Urinary tract infections are the second most common human infection by family of the Enterobacteriaceae, particularly Escherichia coli. According to the increasing antibiotic resistance among strains of E. coli, the purpose of this study was to determine the current pattern and also to investigate changes in the antibiotic resistance patterns of Escherichia coli strains isolated from urinary tract infections in outpatients referring to Nabi-akram hospital in Zahedan city during the past years.
Methods:
This descriptive study was conductedon 87 cases of E. coli isolated from patients with urinary tract infections in a hospital in the city of Zahedan. The drug sensitivity test for antibiotics: imipenem (IPM), gentamicin (GM), ceftazidime (CAZ), nalidixic acid (NA), amikacin (AN), nitrofurantoin (FM) and cotrimoxazole (SXT) for isolates of Escherichia coli was performed.
Results:
Of a total of 87 samples, 70.2% of isolates were women and 29.8% of isolates were isolated from men. Patients' age range was of 12-45 years. The popular resistance to antibiotics: cotrimoxazole (66.6%), nalidixic acid (63%), ceftazidime (44.8%), nitrofurantoin (26.1%), amikacin (19.5%), gentamicin (13.7%) and imipenem (4.5%) were evaluated.
Conclusion:
Based on the results of this study, the antibiotics imipenem and cotrimoxazole had the highest resistance and susceptibility, respectively. Therefore, it is recommended to stop the administration of cotrimoxazole antibiotics to treat urinary tract infections and use Imipenem.
Keywords
Escherichia coli
antibiotic resistance pattern
Urinary tract infections
Outpatient
Subjects
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Journal of Paramedical Sciences & Rehabilitation
Volume 6, Issue 4
Autumn 2017
Pages 73-78