Evaluation of Auditory Cortical Function in Type I Diabetic Patients by Auditory Late ‎Latency Response

Document Type : Original Article

Authors

Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, ‎Tehran, Iran

Abstract

Purpose:
Diabetes is a common disorder which contributes to a variety of complications such as deficits in central auditory nervous system (CANS). Auditory late latency response (ALLR) is a well-established neurophysiological approach in the assessment of CANS performance. This study was aimed to compare ALLR in insulin dependent (Type I) diabetic patients and normal individuals.
Methods:
In this descriptive analytical and non-interventional study, ALLR was measured by using tone burst 1000 Hz on 25 Type I diabetic patients and 25 age, education and sex matched healthy controls include 12 males and 13 female in both groups, with mean age 28.76±4.1 year in patients and 29.68±3.6 year in controls. Data were analyzed by t-test and Pearson correlation tests using SPSS 17 software.
Results:
The mean ALLRs latency and amplitude of the diabetic patients were significantly different when compared with that of normal controls in both genders (p<0.01). Also, there was a strong correlation between ALLR latency and HbA1c and diabetes duration (p<0.01).
Conclusion:
Significant prolongation in latency and significant reduction in amplitude of ALLRs in the diabetic patients shows that cortical auditory information processing is slower than normal individuals.

Keywords


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