Nosocomial urinary tract infections: etiology, risk factors and antimicrobial pattern in Ghaem University Hospital in Mashhad

Saedi, S; Chakerzehi, A; Soltani, N; Honarmand, M; Yazdanpanah, M; Ghazvini, K; Safdari, H

doi:10.22038/jpsr.2013.504

Nosocomial urinary tract infections: etiology, risk factors and antimicrobial pattern in Ghaem University Hospital in Mashhad

Document Type : Original Article

Authors

S Saedi

A Chakerzehi

N Soltani

M Honarmand

M Yazdanpanah

K Ghazvini

H Safdari

10.22038/jpsr.2013.504

Abstract

Purpose:
Nosocomially acquired urinary tract infections (NAUTIs) are common infections in the hospital setting. Since the bacterial spectrum of NUTIs is extensive and the antibiotic resistance is common, we decided to study the incidence of etiology, antibiotic resistance and risk factors of (NAUTIs) in Ghaem University Hospital in Mashhad, Iran from 2009 to2012.
Methods:
The Present study is based on the isolation-identification and determining the antibiotic resistance pattern of (NAUTIs( from 2009 to 2012. Demographic data of patients regarding age, gender, symptoms and signs were collected by a valid questionnaire.
Results:
Among 647 patients with nosocomial infection, the prevalence of NAUTI was 102 (17.2%) during this period. The most frequently isolated micro-organism was Candida spp (20.9%), followed by Escherichia coli (16.3%), Klebsiella sp (15.4%), enterococci and acinetobacter (14.5%). Among antibiotic resistant bacteria, (53.8%) of E. coli were resistant to ampicilin and cefepim. Acinetobacter showed 66.6% resistance to ciprofloxacin, ceftriaxone and cefotaxime.
Conclusion:
Among the isolates, approximately 46% had multidrug resistance to three or more agents and effective antibiotics for treatment of UTIs were nitrofurantoin and norfloxasin in this study.

Keywords

Urinary tract infections

Resistance

Risk Factor

Subjects