Study of Corneal Hysteresis and Corneal Resistance Factor in Pellucid Marginal Corneal Degeneration by Ocular Response Analyzer

Document Type : Original Article

Authors

1 Associate Professor of Ophthalmology, Cornea Research Center, Khatam‐Al‐Anbia Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

2 Professor of Optometry, Department of Optometry, School of Paramedical Science, Mashhad University of Medical Sciences, Mashhad, Iran--Refractive errors research center, School of paramedical sciences, Mashhad University of Medical Sciences, Mashhad, Iran

3 Refractive errors research center, School of paramedical sciences, Mashhad University of Medical Sciences, Mashhad, Iran

4 PhD student of Optometry, Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran

5 5. MSc student of Optometry, Department of Optometry, School of Paramedical Science, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Purpose:
The present research aimed to study the corneal hysteresis (CH) and corneal resistance factor (CRF) in Pellucid Marginal Corneal Degeneration (PMCD) by means of Ocular Response Analyzer (ORA)
Methods:
This retrospective observational study performed based on patients’ medical records from January 2013 to October 2015. A total of 102 eyes from 63 patients with age range of 20 to 50 years were included. Inclusion criteria for this study was diagnosis of PMCD based on clinical and paraclinical evaluations. Exclusion criteria for this study consisted of any other corneal disease, severe dry eye, glaucoma, using any ocular medication, pregnancy or nursing, systemic disease, history of previous eye surgery, older than 50 years and eyes suspect to another corneal ectasia. The data of CH, CRF and other outcomes of ORA were obtained and data analysis was performed using SPSS software for descriptive and analytical statistical methods.
Results:
According to the outcomes of ORA in our study, CH, CRF, Goldmann-correlated intraocular pressure (IOPG) and corneal-compensated intraocular pressure (IOPcc) were (mean ± SD) 9.18±1.47, 8.48±1.72, 12.38±3.42 and 14.58±3.08 respectively. There is no statistically significant difference between male and female for CH (P=0.12), IOPG (P=0.07) and IOPcc (P=0.37) except for CRF (P=0.01).
Conclusion:
These data provide normative values for PMCD measured using the ORA. Corneal biomechanical outcomes of ORA include CH and CRF in PMCD may be employed   for diagnosis and treatment of PMCD. 

Keywords

Main Subjects

References

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Journal of Paramedical Sciences & Rehabilitation
Volume 5, Issue 2
May 2016
Pages 51-57

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