The Survey of the Association of Iron Deficiency in Helicobacter Pylori Infected Patients who referred to a Medical Diagnostic Laboratory in Neyshabour Between September 2015 to March 2016

Document Type : Original Article

Authors

1 MSc in Biology, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran

2 Research Center for HIV/AIDS, HTLV and Viral Hepatitis, Iranian Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran

3 Medical Diagnostic Laboratory of Neyshabour, Center of Medical, Pathological and Genetic Diagnostic Services, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran

Abstract

Purpose:
Helicobacter pylori infection is one of the most common chronic bacterial infections in human worldwide. Recent evidences suggest that iron deficiency and anemia associated with H.pylori. The aim of this study was to evaluate iron deficiency in patients with H. pylori infection who referred to Medical Diagnostic Laboratory of ACECR-Razavi Khorasan in Neyshabur.
Methods:
This Case-control study has performed on 162 patients who referred to Medical Diagnostic Laboratory of ACECR-Razavi Khorasan in Neyshabur and was conducted Between September 2015 to March 2016. Demographic data including age and gender were recorded. Participants were questioned for use of supplemental iron drugs. Based on the amount of IgG antibodies against H.pylori infection by ELISA, all participants were divided into two groups. Then hemoglobin, ferritin, iron and TIBC tests were performed for all samples. Results were analyzed by SPSS software.
Results:
The results showed that there is a significant difference between two groups infected with H.pylori infection and control in hemoglobin, ferritin, iron, TIBC tests (P <0/001). Averages of H.pylori IgG antibody titer, hemoglobin, ferritin, iron and TIBC in patients with H. pylori infection were 86, 12.9, 13, 41.6 and 424, respectively. In healthy individuals (controls), the amounts were 10.2, 14.3, 110, 91 and 362 respectively.
Conclusions:
According to the results of the present study, there is a relationship between H.pylori infection and anemia. Therefore, it would be suggested that doctors and specialists should consider this issue prior to any treatment.

Keywords

Main Subjects

References

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Journal of Paramedical Sciences & Rehabilitation
Volume 6, Issue 1
February 2017
Pages 39-46

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